Iker Casillas (156), Xavi (151) and Raul (142) have made m

BOSTON -- Dozens of times since beginning their work on the brains of former football players, boxers and military members who suffered repeated blows to the head, researchers have announced their findings with slides of damaged tissue, strong words about the danger of concussions and perhaps a call for sports officials to take the issue more seriously.At a Boston University medical conference on Thursday, doctors put a human touch on the often clinical diagnoses, announcing to a room stocked with family members of CTE casualties that former Patriots and Eagles fullback Kevin Turner -- the lead plaintiff in the NFLs concussion lawsuit -- also was a victim of the disease.Theres people there, not just brains, Tamara Alan, executive director of the Kevin Turner Foundation, said as she choked back tears to thank the researchers for their work.With Turners parents in the crowd, neuropathologist Ann McKee said the former Alabama and NFL star had the most severe form of chronic traumatic encephalopathy, a traumatic brain disease linked to repeated hits to the head. CTE likely caused the Lou Gehrigs disease that killed Turner in March at the age of 46, according to McKee.The severity of Mr. Turners CTE was extraordinary and unprecedented for an athlete who died in his 40s, she said.CTE has been linked to repeated brain trauma and diagnosed in hundreds of former football players. It can also cause symptoms of Lou Gehrigs disease, also known as amyotrophic lateral sclerosis, or ALS.Showing slides with evidence of both CTE and ALS in Turners brain, McKee said that its not possible to establish that the CTE caused Lou Gehrigs disease through an autopsy, but this is the best circumstantial evidence we will ever get.After helping Alabama to the national championship in 1992, Turner played eight years in the NFL for New England and Philadelphia. He was diagnosed with ALS in 2010 and pledged his brain to the Concussion Legacy Foundation that year.McKee said Turner had several symptoms associated with CTE, including cognitive and impulse control difficulties. She said it also appears that the disease damaged the motor cortex of his brain when he was young, likely leading to his ALS symptoms.What Kevin Turners case shows is that when you start playing football at 5 years old, and youre successful, it destroys your brain, said Chris Nowinski, a founder of the Concussion Legacy Foundation.Nowinski said children whose brains are still developing shouldnt be playing tackle football, pointing to medical research -- and even football coaches -- who say there would be benefits from playing non-contact football until ninth grade.This is a totally preventable disease, McKee said. Lets start preventing it.Raymond Turner, Kevins father, said Kevins son stopped playing tackle football before resuming when he reached high school. Raymond Turner said he didnt regret that Kevin played football, but he wouldnt have started him on tackle football so early if hed known the risks.Wed probably do it again, Raymond Turner said, just in a safer way.Turner was one of the named plaintiffs from as many as 6,000 potential players who reached a $1 billion settlement with the NFL to monitor more than 20,000 NFL retirees over 65 years old and compensate those with dementia, Alzheimers disease and other serious neurological conditions.Turner also created and served as president of the Kevin Turner Foundation, which seeks to show the potential connections between repeated brain trauma and Lou Gehrigs disease, which causes muscle weakness, paralysis and eventually respiratory failure.In the documentary American Man featured on the foundations website, Turner said he wants to help convince old-school coaches to take concussions seriously.I believe this is the most important thing Ill ever do in my life, other than raising my kids, he said. 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The nimble-footed quarterback got his wish, dashing through the snow and a weary defence all the way into the NCAA record book.Wednesday, March 2 marks 25 years to the day since Ryan Giggs Manchester United debut against Everton at Old Trafford. Then 17, the young Welshman started a journey that would lead to a club-record 963 appearances, including 13 Premier League titles, two Champions Leagues and four FA Cups.Hes since transitioned from the pitch to the dug-out as Louis van Gaals assistant, but to celebrate a quarter-century at the club, Sky Sports takes a look at 25 facts that help define his remarkable time at United... Giggs scored on his full league debut against Man City - Giggs was signed by United on July 9, 1990 and was offered his first professional contract on the day he turned 17 - November 29, 1990.- In his early teenage years, he attended Manchester Citys school of excellence.- Giggs made his debut as a first-half substitute for the injured Denis Irwin against Everton in March 1991. United lost the match 2-0. Giggs is now Louis van Gaals assistant manager - He scored his first senior goal on his full league debut against Man City in a 1-0 win for United at Old Trafford two months later.- That was the first of 672 top-flight appearances for the Red Devils (Division One and Premier League), of which 117 came as a substitute.- His 632 Premier League appearances is the most in the competitions history. Giggs is Uniteds all-time record appearance maker - Giggs scored in all but one of his 22 seasons in the first-team - despite making 22 appearances during his final campaign (2013/14), he failed to find the net.- He took charge as interim player-manager following David Moyes departure, and made his final appearance for United in a 3-1 victory over Hull City at Old Trafford in May 2014. Giggs brought himself on to replace Tom Lawrence after 70 minutes. Then interim manager, Giggs brought himself on for his final appearance against Hull in 2014 - He ended his career with 109 Premier League goals, two more than former team-mate Paul Scholes. That places him 20th in the leagues all-time scoring list.- In the top 20 all-time Premier League top scorers, only two players who have played for a single Premier League club have scored more - Thierry Henry for Arsenal (175) and Steven Gerrard for Liverpool (120). - His club-record 963 appearances is 205 more than second-place Sir Bobby Charlton.- He surpassed Charltons mark of 758 appearances on the same night he won his second Champions League - in Moscow on May 21, 2008 as United beat Chelsea on penalties. Giggs scored what turned out to be the winning spot-kick against Chelsea in the Champions League final - Giggs scored what proved to be the decisive spot-kick in that penalty shoot-out victory over Chelsea.dddddddddddd- In total, he hit 168 goals for the club - good enough for sixth on Uniteds all-time goalscoring chart, and 11 behind George Best in fifth.- His total of 13 Premier League goals during the 1993/94 season was the highest single-season tally of his career.- Giggs won 34 trophies as a player, making him the most decorated in English football history. Giggs came on as a second-half substitute as he won his second Champions League trophy in Moscow - United beat Red Star Belgrade in the 1991 European Super Cup to earn Giggs his first senior trophy, while his last came in the 2013 Community Shield. United beat Wigan 2-0 at Wembley.- He was twice named PFA Young Player of the Year (1991/92, 1992/93), and was named in the PFA Team of the Year six times (1992/93, 1997/98, 2000/01, 2001/02, 2006/07, 2008/09).- Giggs never received a red card while playing for United, although he did get sent off for Wales against Norway in 2001 after two yellow cards. Giggs scored Uniteds first Champions League group stage goal in 1994 - Only Iker Casillas (156), Xavi (151) and Raul (142) have made more Champions League appearances (141).- Giggs is the only player to score in 16 different Champions League campaigns. He scored his first in 1994 against IFK Goteborg and his last against Benfica September 2011.- His strike against Goteborg after 33 minutes on September 14, 1994 was Uniteds first Champions League group stage goal. He added a second in the same game shortly after as United beat their Swedish opponents 4-2. Giggs celebrates FA Cup success with Peter Schmeichel, Paul Scholes and Andrew Cole - His goal against Benfica, at 37 years and 290 days, briefly made Giggs the oldest scorer in Champions League history, but Francesco Tottis strike against Man City in September 2014 broke that record. Totti was 38 years and three days.- France legend and current Real Madrid manager Zinedine Zidane once said of Giggs: If he was French, I would have been on the bench!- Giggs was given an OBE for his services to football in 2007. Also See: Man Utd v Watford preview Utd expect 6pm Liverpool start Man Utd close to 1,000 goals Merse: LVG deserves credit ' ' '